![]() “I had the idea for ‘MANHOLE’ for a long time, but didn’t know how to put it into a song until I got the beat from Gimgigam. While testing a variety of styles has been key to her growth over the past three years, xiangyu says that her recent time with producer Gimgigam has helped her realize new potential. She went on to experiment in the more collaborative medium of music, subsequently releasing 12 singles and an LP under the xiangyu moniker, while playing with genre and songwriting approaches. “From there, I found a new life,” the artist says. Xiangyu refers to the next five years as “the dark years.” She continued to work alone in fashion design, as well as a brief stint trying her hand at office work, before getting back in touch with Fukunaga, who connected her with producer Kenmochi Hidefumi. “I thought she had unique ideas, and I wanted her to know that fashion is not the only outlet in which to express them.” “She was creative and unique already,” says Fukunaga. ![]() As she continues to define her style, she holds herself to relentlessly high standards and, refusing to repeat herself, she has managed to carve out a niche in the industry in which she now operates.Īt the age of 20, studying fashion design at Bunka Fashion College Tokyo, music was never an industry that xiangyu expected to find herself in, until she was approached by Wednesday Campanella manager, Yasutomo Fukunaga. Since jump-starting her career in the music industry three years ago, after departing from the fashion industry, the energetic, almost restless artist has experimented with a variety of sounds. For Kanagawa-native xiangyu, her personal style of expression is constantly evolving. Nature, 475: 59-64.Regardless of the medium, self-expression is central to creativity. (2011)Crystal structure of a copper-transporting PIB-type ATPase. Preben Morth, Lisbeth Birk Møller*, Bjørn Panyella Pedersen, Poul Nissen*. Pontus Gourdon#, Xiang-Yu Liu#, Tina Skjørringe, J. Nature Structural & Molecular Biology,19: 728–730.Ĩ. (2012) The Structural Basis for the Sensing and Binding of Cyclic di-GMP by STING. Yi-He Huang#, Xiangyu Liu#, Xiao-Xia Du, Zheng-Fan Jiang, Xiao-Dong Su. (2017) Mechanism of intracellular allosteric β2AR antagonist revealed by X-ray crystal structure. (2018)Structure-guided development of selective muscarinic M3 acetylcholine receptor antagonists.PNAS.,115(47):12046-12050.Ħ. Heinrich, Kunio Hirata, Xiangyu Liu*, Roger K. Hongtao Liu#, Josefa Hofmann#, Inbar Fish#, Benjamin Schaake, Katrin Eitel, Amelie Bartuschat, Jonas Kaindl, Hannelore Rampp, Ashutosh Banerjee, Harald Hübner, Mary J. Hildebrand, Brian Kobilka*.(2019) Structural insights into the process of GPCR-G protein complex formation.Cell,177(5):1243-1251.ĥ. Tiemann, Yang Du, Hongtao Liu, Kunio Hirata, Xiaoou Sun, Ramon Guixà-González, Jesper M. Xiangyu Liu# * ,Xinyu Xu#, Daniel Hilger#, Philipp Aschauer, Johanna K.S. (2019) Mechanism of β2AR regulation by an intracellular positive allosteric modulator.Science, 364 (6447):1283-1287.Ĥ. Kahsai#, Li-Yin Huang, Biswaranjan Pani, Dean P. (2020) Discovery of an allosteric modulator binding to a conformational hub in the β2 adrenergic receptor. Clark, Rachel Ann Matt, Xinyu Xu, Kunio Hirata, Brian K. Xiangyu Liu#, Jonas Kaindl#, Magdalena Korczynska, Anne Stößel, Daniela Dengler, Markus Stanek, Harald Hübner, Jake Mahoney, Mary J. (2021) Binding pathway determines norepinephrine selectivity for the human β1AR over β2AR. Clark#, Harald Hübner, Kunio Hirata, Roger K.
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